Actively Recruiting
MRI Analysis and Degenerative Spine
Led by Universidade Nova de Lisboa · Updated on 2024-01-30
200
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the use of advanced MRI techniques to study degenerative spinal disease, focusing on assessing the condition of compressed nerve roots. The study aims to identify imaging biomarkers affected by the disease and to understand how these markers change as the disease progresses and after treatment. This observational study includes both healthy volunteers and patients diagnosed with spine disease. Participants will undergo MRI scans at diagnosis, during the course of the disease, and following treatment. These MRI images will be analyzed by two neuroradiologists using advanced imaging methods to gather detailed information about the spine and nerve roots. The study does not involve treatment assignment but focuses on diagnostic data collection and analysis. During the study, participants will be evaluated over an 18-month period, with researchers measuring outcomes such as the Oswestry Disability Index (ODI) and lumbar pain intensity. Participants will be asked to attend scheduled MRI assessments and provide consent for data collection. The goal is to track disease progression and treatment impact through imaging and clinical measures, with safety monitoring throughout the study period.
CONDITIONS
Brief Title
MRI Analysis and Degenerative Spine
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 50 and 85 years
- Diagnosis of spinal disease by clinical and imagiological criteria
- Disease duration longer than 3 months
- Ability to give consent
- Fluent Portuguese speaker
You will not qualify if you...
- Previous spine surgery
- Spinal instability
- Neurological disease that may affect walking
- Known orthopedic conditions causing significant gait impairment
- Dementia or developmental disorder with cognitive impairment
- Inability to give consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 18 months
Participants undergo MRI studies at diagnosis, during disease evolution, and after treatment to analyze spine conditions using advanced imaging techniques.
MRI studies at diagnosis, during disease evolution, and after treatment
Duration - Up to 18 months
Participants are monitored for lumbar pain intensity and disability over the course of the study.
Trial Site Locations
Total: 1 location
1
Hospital da Luz Setúbal
Setúbal, Portugal, 2900-722
Actively Recruiting
Research Team
N
Nuno A.R. Cristino, M.D.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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