Evaluation of Cognitive, Neurological, and Psychosocial Health in Adults with Obstructive Sleep Apnea Before and After Three Weeks of Ventilotherapy

What this Trial Is About

Researchers are evaluating multiple aspects of health in patients with Obstructive Sleep Apnea Syndrome OSAS, focusing on changes before and after three weeks of ventilotherapy. The study aims to understand how ventilotherapy may affect cognitive performance, blood markers linked to neurodegeneration, and psychosocial wellbeing in these patients. This observational research highlights the importance of a holistic approach to OSAS treatment, as cognitive and psychosocial difficulties are common but not well understood. Participants will undergo ventilotherapy using a breathing support device during sleep for three weeks. The study compares patients health before and after this treatment period, examining various cognitive functions such as memory, attention, decision making, and planning. Blood samples will be collected to assess biomarkers related to neurodegeneration, and patients will complete self-reported questionnaires on psychosocial wellbeing and quality of life. During the study, patients will complete neuropsychological assessments, blood sampling, and psychosocial questionnaires at the start and after three weeks of ventilotherapy. Researchers will measure cognitive functioning, selective attention, memory, visuo-spatial abilities, inhibition, planning, decision making, neurodegeneration biomarkers, psychosocial wellbeing, and quality of life. The study is expected to provide comprehensive insights into the broader effects of ventilotherapy over this three-week period.

Multidimensional Evaluation of Patients' Affected by Obstructive Apnea Syndrome (OSAS) Before and After Ventilotherapy