Actively Recruiting
Multifrequency MRE in Evaluation of Chronic Kidney Diseases
Led by Shengjing Hospital · Updated on 2026-02-10
200
Participants Needed
1
Research Sites
243 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Chronic Kidney Disease (CKD) is a major public health issue, leading to high mortality and the necessity for renal replacement therapy. Kidney fibrosis, resulting from chronic damage to kidney tissue, significantly determines CKD outcomes. Kidney biopsy, the gold standard for assessing fibrosis, is invasive and limited in its ability to reflect the heterogeneous nature of fibrosis. Consequently, there is growing interest in noninvasive methods, particularly Magnetic Resonance Elastography (MRE). MRE, which evaluates tissue stiffness, has shown potential for assessing kidney fibrosis. This study aims to use multifrequency MRE to assess renal fibrosis, focusing particularly on the early stages of CKD, to enhance understanding of its progression and relationship to clinical outcomes.
CONDITIONS
Official Title
Multifrequency MRE in Evaluation of Chronic Kidney Diseases
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults diagnosed with Chronic Kidney Disease (CKD) according to 2024 KDIGO guidelines, with elevated serum creatinine or abnormal protein levels in urine
- Renal MRI performed within 7 days before or after a kidney biopsy
You will not qualify if you...
- History of genitourinary cancer, polycystic kidney disease, kidney transplant, or acute kidney failure
- Any contraindications to MRI examination
- Poor quality MRI images
- Kidney deformity or severe swelling of the kidney (hydronephrosis) seen on MRI
- Poorly defined boundary between kidney cortex and medulla on imaging
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shengjing Hospital of China Medical University
Shenyang, Liaoning, China, 110004
Actively Recruiting
Research Team
Y
yu shi, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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