A comparison of thrombolytic therapy with primary coronary angioplasty for acute myocardial infarction. Myocardial Infarction Triage and Intervention Investigators.
N R Every, L S Parsons, M Hlatky...
https://pubmed.ncbi.nlm.nih.gov/8857004Completed
Phase 3
Age: 35Years - 71Years
All Genders
ID00000468
Led by University of Washington · Updated on 2016-02-09
N/A
Participants Needed
N/A
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of Washington
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
To determine the practicality, benefit, and safety of paramedic administration of thrombolytic therapy for acute myocardial infarction. The feasibility of paramedics correctly identifying candidates for thrombolytic therapy following myocardial infarction was assessed in Phase I. In Phase II, pre-hospital thrombolytic therapy was compared with in-hospital thrombolytic therapy.
CONDITIONS
Official Title
Myocardial Infarction Triage and Intervention Project (MITI)
Who Can Participate
Age: 35Years - 71Years
All Genders
Eligibility Criteria
You may qualify if you...
Men and women, ages 35 to 71, with chest pain of between 15 minutes and 6 hours duration, systolic blood pressure of more than 80 mm Hg and less than 200 mm Hg, and a diastolic blood pressure of less than 120 mm Hg. (Phase I).
Men and women with m
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Site Locations not provided
Location information for this trial is currently unavailable.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
TREATMENT
Number of Arms
0
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Published Research Related To This Trial
Characteristics, management, and outcome of patients with acute myocardial infarction treated with bypass surgery. Myocardial Infarction Triage and Intervention Investigators.
N R Every, C Maynard, R P Cochran...
https://pubmed.ncbi.nlm.nih.gov/8901724Myocardial Infarction Triage and Intervention Project--phase I: patient characteristics and feasibility of prehospital initiation of thrombolytic therapy.
W D Weaver, M S Eisenberg, J S Martin...
https://pubmed.ncbi.nlm.nih.gov/2312978Early recognition and treatment of the patient suffering from acute myocardial infarction. A description of the Myocardial Infarction Triage and Intervention Project.
J S Martin, P E Litwin, W D Weaver
https://pubmed.ncbi.nlm.nih.gov/2096873The potential for prehospital thrombolytic therapy.
J W Kennedy, W D Weaver
https://pubmed.ncbi.nlm.nih.gov/2208814Accuracy of computer-interpreted electrocardiography in selecting patients for thrombolytic therapy. MITI Project Investigators.
P J Kudenchuk, M T Ho, W D Weaver...
https://pubmed.ncbi.nlm.nih.gov/2033180Effect of age on use of thrombolytic therapy and mortality in acute myocardial infarction. The MITI Project Group.
W D Weaver, P E Litwin, J S Martin...
https://pubmed.ncbi.nlm.nih.gov/1869726Characteristics of black patients admitted to coronary care units in metropolitan Seattle: results from the Myocardial Infarction Triage and Intervention Registry (MITI).
C Maynard, P E Litwin, J S Martin...
https://pubmed.ncbi.nlm.nih.gov/1986498A method of assigning scores to the components of a composite outcome: an example from the MITI trial.
A P Hallstrom, P E Litwin, W D Weaver
https://pubmed.ncbi.nlm.nih.gov/1316829Gender differences in the treatment and outcome of acute myocardial infarction. Results from the Myocardial Infarction Triage and Intervention Registry.
C Maynard, P E Litwin, J S Martin...
https://pubmed.ncbi.nlm.nih.gov/1580724