Actively Recruiting
Myocardial Protection Effect of Simvastatin Undergoing Cardiac Surgery
Led by Sun Yat-sen University · Updated on 2023-04-21
369
Participants Needed
1
Research Sites
726 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Statins have been used to low cholesterol to prevent and treat coronary artery diseases. It was also reported that statins could protect endothelial function and cardiac function during coronary artery bypass graft. The investigators recent found simvastatin reduced myocardial injury during noncoronary artery cardiac surgery in single medical center. The investigators further investigate that whether simvastatin can protect myocardium during noncoronary artery cardiac surgery with cardiopulmonary bypass and improve cardiac function with long term use postoperatively in two medical centers.
CONDITIONS
Official Title
Myocardial Protection Effect of Simvastatin Undergoing Cardiac Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- More than 18-year-old
- Congenital heart disease (not complex)
- Isolated heart valve disease
You will not qualify if you...
- Coronary artery disease
- Allergy for statins
- Poor liver function or Hepatitis
- Pregnant or breastfeeding women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital, Sun Yat-sen University
Guangzhou, Guangdong, China, 510080
Actively Recruiting
Research Team
J
Jing-song Ou, MD, PhD
CONTACT
Z
Zhi-ping Wang, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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