Actively Recruiting

Age: 0 - 18Months
All Genders
NCT06821386

N-Care Project: Enhancing Asian-Pacific Collaboration

Led by National Taiwan University Hospital · Updated on 2025-02-20

70

Participants Needed

1

Research Sites

410 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Through Asian-Pacific multinational collaboration, we aim to utilize third-generation genome sequencing to rapidly diagnose genetic diseases in critically ill infants and young children, achieving the goal of early diagnosis for targeted treatment.

CONDITIONS

Official Title

N-Care Project: Enhancing Asian-Pacific Collaboration

Who Can Participate

Age: 0 - 18Months
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Infant or newborn less than 18 months old
  • Admitted to an intensive care unit
  • Has one or more of the following: multiple birth defects, a major malformation requiring surgery or medication, significantly abnormal EKG, or significant hypotonia
  • Or has high-risk signs from a Brief Resolved Unexplained Event (BRUE) such as recurrent severe infections, prolonged or repeated seizures, unexplained cardiopulmonary resuscitation, or suspected inborn error of metabolism
Not Eligible

You will not qualify if you...

  • Infants with a clear non-genetic diagnosis like infection with normal treatment response, isolated prematurity, transient low blood sugar, isolated unconjugated hyperbilirubinemia, or transient neonatal tachypnea
  • Confirmed genetic diagnosis that explains the illness
  • Families who do not consent to genetic testing or data sharing
  • Infants without enough quality or quantity of DNA sample for sequencing

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

National Taiwan University Hospital

Taipei, Taiwan

Actively Recruiting

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Research Team

N

Ni-Chung Lee, MDPhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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