Actively Recruiting

Age: 18Years +
All Genders
NCT06040073

Natural History of Coronary Atherosclerosis

Led by China National Center for Cardiovascular Diseases · Updated on 2024-11-06

125

Participants Needed

1

Research Sites

129 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The present study sought to explore the predictive value of radial wall strain (RWS, derived solely from angiograms) for coronary artery lesion progression compared with lesion vulnerability assessed by optical coherence tomography (OCT). The lesion progression at 1 year was defined as an increase of ≥20% in diameter stenosis based on quantitative coronary angiography (QCA) evaluation.

CONDITIONS

Official Title

Natural History of Coronary Atherosclerosis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Acute myocardial infarction within 45 days
  • Planned coronary angiography examination or potential interventional treatment
  • Presence of at least one non-flow-restricting lesion in a non-infarct related artery with visually estimated diameter stenosis between 30% and 80% and vessel diameter of 2.5 mm or more
Not Eligible

You will not qualify if you...

  • Cardiogenic shock
  • Pregnant or woman of child-bearing potential
  • Life expectancy less than 1 year due to non-cardiac causes
  • Unable to tolerate contrast agents or anticoagulant/antiplatelet therapy
  • Prior or planned coronary artery bypass grafting (CABG)
  • Poor quality angiographic images that prevent proper vessel assessment
  • Lesions requiring surgical bypass grafting
  • Unable to identify culprit lesion or infarct-related artery according to current evidence

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Lei Song

Beijing, China, 100037

Actively Recruiting

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Research Team

L

Lei Song, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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