Perioperative myocardial infarction has been forgotten.
Danielle Menosi Gualandro, Bruno Caramelli, Pai Ching Yu...
https://pubmed.ncbi.nlm.nih.gov/18452792Actively Recruiting
Led by Sohag University · Updated on 2024-07-09
100
Participants Needed
1
Research Sites
N/A
Total Duration
Acute myocardial infarction (AMI), commonly known as a heart attack, is a serious and often fatal emergency and is the leading cause of death worldwide. The condition mainly results from atherosclerosis, a long-term buildup of plaques in the coronary arteries, which involves complex immune and inflammatory processes. Researchers are interested in studying inflammatory markers to better understand and predict outcomes in ST-segment elevation myocardial infarction (STEMI). This study focuses on two relatively inexpensive markers, the neutrophil-to-lymphocyte ratio (NLR) and C-reactive protein (CRP), which may help assess cardiovascular risk and prognosis, especially in low-resource settings. This observational study evaluates the role of NLR and CRP levels as diagnostic tests in patients with STEMI. Participants are grouped based on whether they have elevated or normal levels of these markers. The study tracks these markers over six months to explore their predictive value for immediate and short-term prognosis after STEMI. The research involves measuring these inflammatory markers at admission and during follow-up. Participants will undergo blood tests to measure NLR and CRP and will be monitored for six months to assess their cardiovascular outcomes. Researchers will review these markers to determine their relationship with complications after STEMI. The study aims to provide cost-effective tools for risk stratification and prognosis in acute myocardial infarction. Participation involves regular follow-ups and blood sample collection to monitor the markers and health status over the study period.
CONDITIONS
NLR AND CRP Useful as Cost-Effective Preliminary Prognostic Markers in ST-Elevation Myocardial Infarction
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - At baseline
Participants undergo blood tests to measure neutrophil-to-lymphocyte ratio (NLR) and C-reactive protein (CRP) levels for prognostic assessment of ST-elevation myocardial infarction.
1 visit (in-person)
Duration - Up to 6 months
Participants are observed to assess the predictive value of NLR and CRP levels on myocardial infarction outcomes over time.
Follow-up visits as needed for outcome assessment
Total: 1 location
1
Sohag university hospital
Sohag, Egypt
Actively Recruiting
A
Albair Y Kaiser, Resident
S
Sharaf El-DEEN Sh Abd-Allah, Professor
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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