Dietitian-Led Nutritional Program to Improve Constipation in Adults with Parkinsons Disease

What this Trial Is About

Researchers are evaluating whether a dietitian-guided nutritional intervention can improve constipation symptoms in adults with Parkinsons disease PD who have functional constipation. This study aims to determine if this tailored diet plan can increase weekly bowel movements and positively affect gut microbiota, dietary intake, and nutritional status compared to a control group receiving general dietary guidance after the study. The trial focuses on these important questions to better manage bowel function issues in people with PD. Participants in the intervention group will receive a diet plan created by a registered dietitian based on Dietary Reference Intakes and adapted to the needs of individuals with PD and constipation. They will have follow-up sessions with the dietitian over a 3-month period. The control group will not receive individualized nutritional support during the study but will get general dietary guidance after the 3-month study period. The study uses a randomized, parallel design to compare these groups. During the study, participants will complete assessments at the start, midpoint, and end to evaluate bowel function, constipation symptoms, gut microbiota composition, nutritional status, and diet quality. The main outcome measured is the change in weekly bowel movement frequency from baseline to 90 days. Secondary outcomes include changes in gut microbial taxa. The study will monitor participants over the 3-month intervention period, with safety and adherence overseen by the research team.

Nutritional Intervention for Constipation Symptoms in Patients With Parkinson's Disease