Actively Recruiting
Observational Study on the Impact of Obstructive Sleep Apnea on Executive Function and Empathy Development in Children
Led by Children's Hospital of Soochow University · Updated on 2026-01-26
150
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating how obstructive sleep apnea (OSA) affects executive function and empathy development in children aged 3 to 12 years. This observational study compares different treatments—surgical and pharmacological—for children with mild OSA, while also exploring EEG biomarkers that may indicate neurological damage. The goal is to understand cognitive and emotional changes over a year and provide guidance for treatment choices. Children diagnosed with mild, moderate, or severe OSA are grouped by disease severity and treatment type. Those with mild OSA receive either adenotonsillectomy surgery or conservative pharmacological treatment with nasal corticosteroids and leukotriene receptor antagonists. Children with moderate or severe OSA undergo adenotonsillectomy. A healthy control group without sleep disorders is included for comparison. Assessments occur at the start, 6 months, and 12 months after treatment or observation. Participants undergo behavioral tests, EEG recordings, and parent questionnaires to measure executive function, empathy, working memory, and sleep habits. Researchers track the Obstructive Apnea-Hypopnea Index and oxygen saturation during sleep to monitor disease severity. The study lasts 12 months, with evaluations at multiple points to observe changes and identify potential EEG signs of neurological impact in children with OSA.
CONDITIONS
Brief Title
Observational Study on the Impact of Obstructive Sleep Apnea on Executive Function and Empathy Development in Children
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children aged 3 to 12 years
- Diagnosed with obstructive sleep apnea due to adenoid and/or tonsillar hypertrophy
- IQ of 85 or higher
- Parental consent for participation
You will not qualify if you...
- Presence of other primary sleep disorders such as narcolepsy or restless leg syndrome
- Developmental delay, epilepsy, or other neurological or metabolic disorders
- Chronic diseases or history of head trauma
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Baseline assessment period
Participants undergo assessments including behavioral tests, EEG, and questionnaires to evaluate executive function, empathy, and sleep parameters at baseline.
1 visit (in-person)
Duration - 12 months
Participants are observed and assessed over time to monitor changes in executive function, empathy, and sleep parameters at 6 months and 12 months post-baseline.
2 visits (in-person) at 6 months and 12 months
Trial Site Locations
Total: 1 location
1
Children's Hospital of Soochow University
Suzhou, Jiangsu, China, 215233
Actively Recruiting
Research Team
T
Tingyu Rong, Doctor
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
5
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