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Comparing Oral and Intravenous Beta-Blockers and the Effect of Music on Heart Rate Control During Cardiac CT
Led by Karolinska University Hospital · Updated on 2025-03-17
240
Participants Needed
1
Research Sites
99 weeks
Total Duration
AI-Summary
What this Trial Is About
This research aims to find the best way to lower heart rate before a special type of heart imaging called Computed Tomography of the coronary vessels CCTA. The study compares four different methods to reduce heart rate, which is important because a high heart rate can make imaging harder and may increase radiation exposure. The study also looks at whether listening to music during the procedure helps improve patient comfort and experience. Participants are randomly assigned to one of four groups. One group receives oral beta-blocker medication Seloken, another gets intravenous Metoprolol directly at the CT table, a third group rests for one hour before receiving intravenous Metoprolol, and the last group receives oral Seloken plus intravenous Metoprolol along with calming music before and during the CT scan. The doses and timing vary, including a waiting period where applicable. During the study, heart rate is monitored from enrollment until the end of the examination, which lasts about 1.5 hours. Participants also report their feelings of anxiety and comfort using visual scales. Researchers measure heart rate stability, reduction, and participant-reported experiences to determine which preparation method works best. The study includes 240 adults and involves standard clinical assessments and heart rate monitoring throughout the procedure.
CONDITIONS
Brief Title
Optimization of Patient Preparation and Imaging Techniques for Cardiac CT
Research Team
A
Aziza Adem Adem, MSc
A
Anders Svensson-Marcial, PhD
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