Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06879769

Optimization of Patient Preparation and Imaging Techniques for Cardiac CT

Led by Karolinska University Hospital · Updated on 2025-03-17

240

Participants Needed

1

Research Sites

99 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to find the best way to lower heart rate before a special type of heart imaging called Computed Tomography of the coronary vessels (CCTA). The study compares four different methods to reduce heart rate, which is important because a high heart rate can make imaging harder and may increase radiation exposure. The study also looks at whether listening to music during the procedure helps improve patient comfort and experience. Participants are randomly assigned to one of four groups. One group receives oral beta-blocker medication (Seloken), another gets intravenous Metoprolol directly at the CT table, a third group rests for one hour before receiving intravenous Metoprolol, and the last group receives oral Seloken plus intravenous Metoprolol along with calming music before and during the CT scan. The doses and timing vary, including a waiting period where applicable. During the study, heart rate is monitored from enrollment until the end of the examination, which lasts about 1.5 hours. Participants also report their feelings of anxiety and comfort using visual scales. Researchers measure heart rate stability, reduction, and participant-reported experiences to determine which preparation method works best. The study includes 240 adults and involves standard clinical assessments and heart rate monitoring throughout the procedure.

CONDITIONS

Brief Title

Optimization of Patient Preparation and Imaging Techniques for Cardiac CT

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participant with a preexisting referral for a Cardiac CT examination
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Age under 18 years
  • Atrial fibrillation
  • Pacemaker
  • Participation in clinical drug trials
  • Contraindications to beta-blockers
  • Severe medical conditions
  • Challenges in comprehending study information
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Participants are screened before enrollment.

Treatment

Duration - Approximately 1.5 hours from enrollment to end of examination

Participants receive beta-blocker interventions and cardiac CT scans according to their assigned group. This includes oral and/or intravenous Metoprolol administration, with some groups resting for 1 hour before intravenous dosing, and one group also listening to calming music before and during the scan.

1 visit (in-person) including preparation and cardiac CT imaging

Trial Site Locations

Total: 1 location

1

ME Radiologi Huddinge, Karolinska University Hospital

Stockholm, Huddinge, Sweden, 141 86

Actively Recruiting

Loading map...

Research Team

A

Aziza Adem Adem, MSc

A

Anders Svensson-Marcial, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

4

Similar Trials

Assessing the Impact of Intensification of Lipid Lowering Th...

Homozygous Familial Hypercholesterolemia (HoFH)

Actively Recruiting

13 locations

Improving the Clinical Management of Stable Chest Pain Using...

Coronary Computed Tomography Angiography

Actively Recruiting

4 locations

Changes in Plaque Characteristics After Short-term Statin Th...

Coronary Artery Disease

Actively Recruiting

1 location

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here