Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06879769

Optimization of Patient Preparation and Imaging Techniques for Cardiac CT

Led by Karolinska University Hospital · Updated on 2025-03-17

240

Participants Needed

1

Research Sites

360 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to compare four different methods of reducing heart rate before cardiac imaging. The diagnostic imaging technique used in this study is called Computed Tomography (CT) of the coronary vessels (CCTA). Globally, approximately one-third of patients experience heart-related conditions. Because the heart is a moving organ, imaging presents challenges. A higher heart rate requires increased scanning power, which results in more images and, in some cases, higher radiation exposure that may be harmful. To address this issue, beta-blocker medication is administered before the examination to lower the heart rate. This medication can be given orally, intravenously, or both. While this approach is effective, the most optimal method remains uncertain. The objectives of this study are: * To determine whether oral administration of beta-blockers is as effective as intravenous administration in maintaining a stable heart rate during CT imaging. * To assess whether listening to music during the procedure improves patient comfort and overall experience. Participants will: * Be randomly assigned to one of four groups: * One group will receive beta-blocker medication orally. * Another group will receive beta-blocker medication intravenously. * One group will listen to music during the procedure. Participants will report their sensations and experiences before, during, and after the examination. The study investigators will compare the effectiveness of oral and intravenous beta-blockers, as well as the impact of music, in terms of: * Heart rate stability and reduction. * Participant-reported comfort and overall experience.

CONDITIONS

Official Title

Optimization of Patient Preparation and Imaging Techniques for Cardiac CT

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participant with a preexisting referral for a Cardiac CT examination
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Age under 18 years
  • Atrial fibrillation
  • Pacemaker
  • Participation in clinical drug trials
  • Contraindications to beta-blockers
  • Severe medical conditions
  • Challenges in comprehending study information
  • Pregnancy

AI-Screening

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Trial Site Locations

Total: 1 location

1

ME Radiologi Huddinge, Karolinska University Hospital

Stockholm, Huddinge, Sweden, 141 86

Actively Recruiting

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Research Team

A

Aziza Adem Adem, MSc

CONTACT

A

Anders Svensson-Marcial, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

4

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