Validation and Comparison of PROMISE and CONFIRM Model to Predict High-Risk Coronary Artery Disease in Symptomatic and Diabetes Mellitus Patients.
Hantao Jiang, Jinping Feng, Chao Feng...
https://pubmed.ncbi.nlm.nih.gov/35345247/Actively Recruiting
Led by Tianjin Chest Hospital · Updated on 2024-03-28
50000
Participants Needed
4
Research Sites
N/A
Total Duration
Researchers are enrolling patients who have stable chest pain suspected to be caused by obstructive coronary artery disease. These patients are referred for coronary computed tomography angiography CCTA, a detailed heart imaging test, to better understand their condition. The study aims to see if using CCTA images can improve how doctors manage stable chest pain, potentially leading to fewer major heart-related problems and better decisions about further tests and treatments. All participants receive CCTA scans following standard guidelines and hospital protocols. The images are analyzed using specialized software to examine the coronary arteries structure, function, and tissue characteristics. This observational study collects detailed imaging data to explore how this information can guide clinical decisions and improve patient outcomes. Participants are monitored over a long period, up to 10 years, to track important heart events such as major adverse cardiovascular events, invasive coronary angiography, medication use, revascularization procedures, death, stroke, cardiac death, and heart attacks. This extended follow-up helps researchers understand the impact of CCTA-based management on patient health and treatment effectiveness.
CONDITIONS
CCTA Improves Clinical Management of Stable Chest Pain
J
Jia Zhou
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Tianjin Chest Hospital
Lead Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Single time point
Participants undergo coronary computed tomography angiography (CCTA) to assess stable chest pain according to established guidelines and local protocols.
1 visit (in-person)
Duration - Up to 10 years
Participants are monitored for major cardiovascular events and clinical outcomes over an extended period.
Periodic follow-up visits over 10 years
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Lead Sponsor