Personalized Positive End-Expiratory Pressure Using Electrical Impedance Tomography in Adults Undergoing Laparoscopic and Robotic Abdominal Surgery

What this Trial Is About

Laparoscopic surgery is widely used because it is less invasive, leading to less pain after surgery, shorter hospital stays, and quicker recovery compared to traditional open surgery. However, patients undergoing these procedures still face risks of breathing problems after surgery due to factors like general anesthesia, body positioning during surgery, and the use of CO2 gas in the abdomen. This study explores using a personalized approach to setting positive end-expiratory pressure PEEP, a ventilation technique that helps keep lungs open, guided by Electrical Impedance Tomography EIT, to improve lung function during laparoscopic and robotic surgeries. Participants will be randomly assigned to one of two groups. One group will receive standard PEEP settings decided by clinicians, while the other group will have PEEP levels personalized using a PEEP trial guided by the PulmoVista 500 EIT device. This device monitors lung ventilation in real time and helps find the best PEEP level to reduce lung collapse without causing overinflation. The personalized PEEP is adjusted during surgery and maintained throughout the procedure to optimize lung function. During the study, participants will be closely monitored at several time points, including before and after anesthesia induction, during surgery in specific positions, and after PEEP adjustments. Researchers will measure static respiratory system compliance, which reflects how well the lungs can expand, as the main outcome. The study will also observe gas exchange and lung function after surgery. The entire process aims to improve respiratory health during and after laparoscopic surgery while tracking safety and recovery progress, with the study concluding in November 2026.

PEEP Titration Guided by Electrical Impedance Tomography in Laparoscopic Surgery The PEaRL Study