Actively Recruiting

Phase Not Applicable
Age: 75Years +
All Genders
ID06904703

Combination of Pericapsular Nerve Group and Lumbar Erector Spinae Plane Blocks for Geriatrics Undergoing Total Hip Arthroplasty Under General Anesthesia: A Randomized Controlled Trial

Led by Tanta University · Updated on 2025-04-01

120

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of pericapsular nerve group and erector spinae plane blocks as additional treatments to general anesthesia in older adults undergoing total hip arthroplasty. This surgery is commonly performed to improve function and quality of life but can cause significant postoperative pain. General anesthesia is often used for patients with complex health conditions, though it may increase risks such as delirium and delayed mobility in elderly patients. The study compares three groups: one receiving only general anesthesia, one receiving general anesthesia plus the erector spinae plane block, and one receiving general anesthesia combined with both the erector spinae plane block and the pericapsular nerve block. These nerve blocks target specific nerves around the hip to provide pain relief, potentially reducing the need for other pain medications and minimizing complications. Participants will undergo detailed monitoring during surgery, including measuring the amount of sevoflurane used to maintain a targeted brain activity level. Postoperative assessments will include pain levels, opioid consumption, blood pressure, heart rate, patient satisfaction, and any complications within 24 hours after surgery. The study involves random assignment to groups, double-blind methods, and will follow patients through their surgery and recovery period starting from December 2024.

CONDITIONS

Brief Title

Pericapsular Nerve Group and Lumbar Erector Spinae Plane Blocks for Geriatrics Undergoing Total Hip Arthroplasty

Who Can Participate

Age: 75Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged over 75 years
  • Both sexes
  • American Society of Anesthesiologists (ASA) classification I-III
  • Undergoing total hip arthroplasty under general anesthesia
Not Eligible

You will not qualify if you...

  • Patient refusal
  • Body mass index (BMI) over 30 kg/m2
  • Allergy to local anesthesia drugs
  • Infection at the site of intervention
  • Coagulopathies
  • Preexisting advanced diseases of the kidney or liver

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Up to 2 hours (duration of surgery)

Participants receive general anesthesia with or without erector spinae plane block and pericapsular nerve block during total hip arthroplasty surgery.

1 surgical visit (in-person)

Post-operative Follow-up

Duration - 24 hours postoperatively

Participants are monitored for pain, opioid consumption, vital signs, satisfaction, and complications for 24 hours after surgery.

1 follow-up visit (in-person)

Trial Site Locations

Total: 1 location

1

Faculty of Medicine

Tanta, Egypt, 31527

Actively Recruiting

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Research Team

M

Mai El Hamada, MSc

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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