Actively Recruiting
Analysis of Deep Brain Nuclei LFP and Cortical EEG Signals During the Recovery From General Anesthesia
Led by Ruijin Hospital · Updated on 2024-05-13
42
Participants Needed
1
Research Sites
126 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The correlations of deep brain nuclei firing and cerebral cortex activity during recovery from general anesthesia is unclear. In this study, the local field potential (LFP) from the deep brain nuclei and the scalp electroencephalogram (EEG) of the frontal cortex were recorded from patients undergoing deep brain stimulation (DBS) surgery during the recovery from general anesthesia, in order to explore the changes and relevance of deep brain nuclei firing and cortex activity during the recovery of consciousness from general anesthesia .
CONDITIONS
Official Title
Analysis of Deep Brain Nuclei LFP and Cortical EEG Signals During the Recovery From General Anesthesia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 75 years
- ASA classification I to III
- Meet the indications for deep brain stimulation (DBS) surgery
- Right-handed with normal listening and speaking abilities
- Provide informed consent and cooperate with researchers
You will not qualify if you...
- Cognitive impairment with Montreal Cognitive Assessment score less than 26
- Severe depression with Beck Depression Inventory score 25 or higher
- Dysfunction of important organs such as heart, lungs, liver, or kidneys, or unstable vital signs
- Expected to enter intensive care unit after surgery
- Alcohol or drug dependence
- General anesthesia within one month before surgery or known allergy to general anesthetics
- DBS surgery lasting more than 4 hours
- Pregnancy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Ruijin Hospital Shanghai Jiaotong University School of Medicine
Shanghai, Shanghai Municipality, China, 20025
Actively Recruiting
Research Team
X
Xin Ma, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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