Actively Recruiting
Analgesic Efficacy of Quadro-Iliac Plane Block Versus Erector Spinae Plane in Total Hip Arthroplasty: A Randomized Non-Inferiority Trial
Led by Tanta University · Updated on 2026-04-21
76
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
The trial investigates pain management techniques after total hip arthroplasty (THA), a common surgery for older adults to relieve hip pain and improve joint function. Researchers are comparing two nerve block methods, the Quadro-Iliac Plane Block (QIPB) and the Erector Spinae Plane Block (ESPB), to assess their effectiveness in reducing postoperative pain and opioid use. The study addresses concerns about opioid side effects such as nausea and dependence. Participants receive either the QIPB or ESPB, each involving an injection of 20ml of 0.25% bupivacaine on the side of surgery. These blocks aim to numb nerves to control pain after surgery. The study is randomized and double-blind, meaning participants are assigned randomly to one of the two groups and neither participants nor researchers know the assignment during the trial. During the first 24 hours after surgery, participants are monitored for how long it takes before they need extra pain relief, the total amount of morphine used, their pain levels, quality of recovery, and any side effects. Various assessments track these outcomes to compare the two treatments. This comprehensive monitoring helps evaluate which block may better manage pain with fewer complications.
CONDITIONS
Brief Title
Analgesic Efficacy of Quadro-Iliac Plane Block Versus Erector Spinae Plane in Total Hip Arthroplasty
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 63 18 years
- Both sexes
- American Society of Anesthesiology (ASA) physical status I to III
- Undergoing total hip arthroplasty under spinal anesthesia
You will not qualify if you...
- History of allergies to local anesthetics
- Opioid dependency
- Body mass index (BMI) greater than 35 kg/m2
- Cognitive impairment
- Bleeding or coagulation disorders
- Psychiatric and neurological disorders
- Local infection at the injection site
- Severe heart, lung, liver, or kidney dysfunction
- Emergency surgery planned or performed
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - During surgery and immediate postoperative period
Participants receive either a Quadro-iliac plane block or an Erector spinae plane block as part of their total hip arthroplasty surgery to manage postoperative pain.
1 surgical visit and immediate postoperative care
Duration - 24 hours postoperatively
Participants are monitored for pain levels, morphine consumption, quality of recovery, and adverse events up to 24 hours after surgery.
Approximately 1 follow-up visit within 24 hours
Trial Site Locations
Total: 1 location
1
Tanta University
Tanta, El-Gharbia, Egypt, 31527
Actively Recruiting
Research Team
M
Mohammed S Elsharkawy, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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