Actively Recruiting

Age: 18Years +
All Genders
ID07338929

Physical Performance Assessment in Kidney Transplant Evaluation Using the Short Physical Performance Battery (SPPB)

Led by University Hospital, Martin · Updated on 2026-01-14

50

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to understand physical frailty in adults evaluated for kidney transplantation by assessing their physical performance with the Short Physical Performance Battery (SPPB). It compares SPPB scores before listing for transplant, annually during the waiting period, and at 6 and 12 months after transplantation. The study also includes a control group of dialysis patients not eligible for transplant listing to examine differences in physical function and how frailty might affect transplant outcomes and recovery. Participants include adults being evaluated for kidney transplantation who are either placed on the waiting list or considered unsuitable and on dialysis. SPPB assessments will be conducted at baseline, annually during evaluation or waiting, and for transplant recipients at 6 and 12 months after surgery. This approach allows monitoring of physical performance changes over time in both groups. During the study, participants will undergo regular physical performance testing with the SPPB to measure frailty status. Researchers will track changes in scores ranging from 0 to 12 to categorize frailty levels and analyze how these relate to transplant outcomes like graft function and survival. The study lasts 3 to 5 years, providing insights into frailty progression and potential ways to improve physical function before transplantation.

CONDITIONS

Brief Title

Physical Performance Assessment in Kidney Transplant Evaluation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients (≥18 years) undergoing evaluation for kidney transplantation
  • Patients on dialysis
  • Ability and consent to participate
Not Eligible

You will not qualify if you...

  • Non-adult patients
  • Patients unable to provide informed consent
  • Acute medical conditions prohibiting SPPB assessment

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Baseline and ongoing during evaluation period

Participants undergo physical performance assessments using the Short Physical Performance Battery (SPPB) during their kidney transplant evaluation process.

1 baseline visit and assessments during evaluation

Long-term Monitoring

Duration - 3 to 5 years

Participants are monitored with annual SPPB assessments to track physical performance changes over time, including those on the transplant waiting list and those on dialysis not eligible for transplant.

Annual visits, with additional visits at 6 and 12 months post-transplant for listed participants

Trial Site Locations

Total: 1 location

1

Transplant-nephrology department

Martin, Slovakia, 03601

Actively Recruiting

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Research Team

K

Katarina Sevcikova, MD

A

Andrej Kollar, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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