Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
Healthy Volunteers
NCT07244445

Pistachio Intake and Nutrition-Related Outcomes in Individuals on GLP-1 Therapy

Led by Ian J. Neeland, MD · Updated on 2026-02-20

108

Participants Needed

1

Research Sites

95 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In this study will look at how eating pistachios every day might affect participants weight, how healthy their diet is, and how they feel when eating. Investigators want to see if adding pistachios to meals for 12 weeks helps participants feel fuller, have more energy, and improve body composition. The study will include adults who have been taking GLP-1 medicines like semaglutide or tirzepatide for at least three months. Investigators also want to see if eating pistachios improves overall diet quality and health markers like tiredness and certain levels in blood.

CONDITIONS

Official Title

Pistachio Intake and Nutrition-Related Outcomes in Individuals on GLP-1 Therapy

Who Can Participate

Age: 18Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 80 years
  • Body mass index (BMI) of 30 kg/m2 or higher, or BMI of 27 kg/m2 or higher with at least one weight-related health condition
  • Currently using semaglutide or tirzepatide continuously for at least three months for a clinical reason
  • Remain on GLP-1 therapy at the time of enrollment
Not Eligible

You will not qualify if you...

  • Not using or have a contraindication to GLP-1 receptor agonists
  • Known allergy to nuts
  • Pregnant or breastfeeding
  • Currently incarcerated

AI-Screening

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Trial Site Locations

Total: 1 location

1

University Hospitals Cleveland Medical Center

Clevland, Ohio, United States, 44106

Actively Recruiting

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Research Team

I

Ian Neeland, MD

CONTACT

A

Abigail Raffner, PhD, RD, LD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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