Comparing Low and Standard Pneumoperitoneum Pressures on Lung Health During Laparoscopic Gallbladder Surgery Using Ultrasound

What this Trial Is About

Researchers are studying how different pressures of pneumoperitoneum affect lung function during elective laparoscopic cholecystectomy, a surgery to remove the gallbladder. This trial compares low-pressure 10 mmHg and standard-pressure 14 mmHg pneumoperitoneum to understand their effects on perioperative atelectasis, which is a partial collapse of the lungs that can occur during surgery. Lung ultrasound LUS, a noninvasive bedside tool, is used to assess lung aeration loss caused by pneumoperitoneum during general anesthesia. Participants will be randomly assigned to one of two groups. One group will undergo surgery with pneumoperitoneum pressure maintained at 10 mmHg, and the other at 14 mmHg. Standard anesthesia and surgical protocols are followed for both groups. Lung ultrasound assessments will be performed at three time points after anesthesia induction before pneumoperitoneum starts, at the end of surgery before breathing tube removal, and one hour after arriving in the recovery unit. During the study, participants will have their lung ultrasound scores measured to detect changes in lung aeration. Additional assessments include respiratory mechanics like airway pressure and lung compliance, oxygen levels, postoperative oxygen needs, pain, nausea, and recovery outcomes. These evaluations help researchers understand how the different pressures impact lung function and overall recovery. The study is expected to last from June 2026 to September 2026 with follow-up during the immediate postoperative period.

Pneumoperitoneum Pressure and Lung Ultrasound Atelectasis