An anesthesia-centered bundle to reduce postoperative pulmonary complications: The PRIME-AIR study protocol.
Ana Fernandez-Bustamante, Robert A Parker, Juraj Sprung...
https://pubmed.ncbi.nlm.nih.gov/37023031Actively Recruiting
Led by University of Colorado, Denver · Updated on 2025-04-30
30
Participants Needed
1
Research Sites
26 weeks
Total Duration
U
University of Colorado, Denver
Lead Sponsor
B
Brigham and Women's Hospital
Collaborating Sponsor
Researchers are studying adults who are undergoing elective abdominal surgery and have a moderate to high risk of developing lung problems after surgery. The purpose is to understand how different breathing patterns and physical activities after surgery affect recovery and reduce complications like hypoventilation and other pulmonary issues. This observational study focuses on monitoring these factors to improve care for patients at risk of postoperative pulmonary complications. Participants will have two types of monitoring devices placed on their chest and thigh shortly after surgery in the Post-Anesthesia Care Unit. The ExSpiron device records breathing patterns including breath volume and frequency, while the ActivPAL accelerometer tracks body position and movements like sitting and walking. These devices stay on for up to three days or until the patient can walk 30 meters independently or is discharged from the hospital, whichever happens first. During the study, participants are observed continuously with these monitors to collect data on their breathing and physical activity levels. Researchers will analyze this information along with medications and clinical events to identify links between activity and breathing quality. The study measures outcomes such as hypoventilation during the first three postoperative days and other pulmonary complications through day seven. Participants' activity and breathing data will help inform recommendations for improving postoperative recovery and reducing lung complications after abdominal surgery.
CONDITIONS
Postoperative Respiratory and Activity Monitoring
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 3 days or until the participant is able to walk 30 meters without assistance or discharged from the hospital, whichever comes first.
Participants will have monitoring devices placed on their chest and thigh to record breathing patterns and physical activity after abdominal surgery.
Device placement in the Post-Anesthesia Care Unit and continuous monitoring during hospital stay
Duration - Up to 7 days after surgery
Participants will be observed for clinical complications and physical activity patterns through hospital discharge, including assessment of pulmonary complications and ambulation milestones.
Observational assessments during hospital stay
Total: 1 location
1
UC Health
Aurora, Colorado, United States, 80045
Actively Recruiting
E
Emily G. Helmer
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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