Study Comparing Same-Day Versus No Same-Day Hemodialysis Before Surgery in Adults With End-Stage Kidney Disease

What this Trial Is About

This clinical trial focuses on people with end-stage kidney disease ESKD who are preparing for nonemergent surgical procedures. The study aims to evaluate whether it is feasible and safe to assign participants randomly to one of two hemodialysis schedules before surgery having hemodialysis on the same day as surgery or not. Researchers want to compare these schedules to see if they are similar in terms of scheduling feasibility and safety. Participants will be assigned to either receive hemodialysis on the morning of their surgery day or not receive hemodialysis on that same day. The study uses these two groups to compare the effects and safety of the timing of hemodialysis before surgery. The study period for each participant lasts about two months, including the time before and after surgery. During the study, participants will answer health-related questions up to four weeks before and four weeks after surgery. Researchers will monitor the time between the last hemodialysis session and surgery, as well as any complications such as electrolyte problems, volume overload requiring extra hemodialysis, surgery rescheduling, or higher levels of postoperative care. The study team will carefully observe these outcomes for up to one day after surgery.

Preoperative Hemodialysis Timing in Patients With End-Stage Kidney Disease: The POD-ESKD Pilot Trial