Actively Recruiting
Prevalence and Characteristics of Restless Leg Syndrome in Thai Patients With Parkinson's Disease
Led by Siriraj Hospital · Updated on 2025-05-15
310
Participants Needed
2
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by pathologic intraneuronal alpha-synuclein-positive Lewy bodies and neuronal cell loss. The cardinal clinical symptoms and signs of PD are bradykinesia, rigidity, tremor, postural instability, and freezing attacks. The prevalence of PD increases with age, affecting 1-2% of the population over the age of 65 years, and 3% of those over 85 years. Restless legs syndrome (RLS) represents disturbing symptoms in lower limbs that lead to the urge to move, occurring in rest periods. Movements can partially or completely relieve these abnormal feelings. In 2014, the International RLS Study Group (IRLSSG) established five mandatory criteria for the diagnosis of RLS. Several studies supported that RLS and PD may share pathophysiological mechanisms.
CONDITIONS
Official Title
Prevalence and Characteristics of Restless Leg Syndrome in Thai Patients With Parkinson's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with Parkinson's disease aged from 18 to 80 years who met the United Kingdom Parkinson's Disease Society (UKPDS) Brain Bank Diagnostic criteria.
You will not qualify if you...
- Patients with atypical or secondary parkinsonism.
- Patients with Mini-mental status exam (MMSE) less than 24 of 30.
- Patients with secondary causes of restless leg syndrome including end-stage renal disease, iron deficiency anemia and pregnancy.
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Siriraj Hospital, Mahidol University
Bangkok, Bangkok, Thailand, 10700
Actively Recruiting
2
Siriraj Hospital, Mahidol University
Bangkok, Thailand, Thailand, 10310
Actively Recruiting
Research Team
J
Jindapa Srikajon, Doctor of Medicine
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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