Actively Recruiting
Prevalence, Determinants and Natural History of Frailty and Pre-frailty in People Over the Age of 65 Years in a Prospective 5-year Observation
Led by The Opole University of Technology · Updated on 2020-08-19
1093
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying frailty syndrome, a condition affecting elderly individuals characterized by reduced ability to respond to stress and associated with physical, psychological, and social decline. This study focuses on elderly people over 65 living independently, aiming to understand factors that lead to frailty and how it affects survival, particularly examining cardiovascular and autonomic nervous system changes linked to frailty. The research considers a multidimensional approach to frailty, reflecting the complex functional decline seen in aging individuals. The study involves detailed heart examinations using echocardiography to assess age-related changes in heart function and size. It also measures autonomic nervous system activity through continuous non-invasive monitoring of blood pressure, heart rate, and respiration. Participants will undergo routine medical exams, cognitive and psychological evaluations, nutritional status assessments, daily living activities reviews, and fall risk evaluations. These comprehensive assessments are designed to capture a broad picture of frailty and its determinants. Participants will be followed for five years with re-examinations at two and five years to monitor frailty progression, independence, and survival status via national health records. The study measures risk factors for frailty development, mortality, and functional decline using various clinical and functional tests, including cognitive screening and physical stability assessments. This long-term observation aims to clarify the natural course of frailty and inform strategies to prevent or treat it in the elderly population.
CONDITIONS
Brief Title
Prevalence, Determinants and Natural History of Frailty and Pre-frailty in Elderly People
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Community dwelling elderly individuals over the age of 65 years who get around by themselves.
You will not qualify if you...
- Institutionalization
- Inability to move around
- Terminal diseases with an anticipated survival of less than 1 year.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - At study entry during the first examination
Participants undergo comprehensive assessments including echocardiography, cardiac autonomic system evaluation, routine medical examination, ECG, body measurements, cognitive and psychological evaluations, nutritional assessment, daily living activities assessment, and fall risk evaluation.
1 baseline visit (in-person)
Duration - Up to 5 years
Participants are followed over 5 years to observe frailty and disability development, survival, and transitions in frailty status through periodic re-examinations and registry checks.
Re-examinations at 2 years and 5 years
Trial Site Locations
Total: 1 location
1
Faculty of Physical Education and Physiotherapy, Opole University of Technology
Opole, Poland, 45-758
Actively Recruiting
Research Team
J
Jerzy Sacha, MD, PhD
Z
Zbigniew Borysiuk, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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