Actively Recruiting
A Combined Multidomain Intervention to Prevent Cognitive Decline Associated With Cardiovascular Risk Factors.
Led by Louis Bherer · Updated on 2025-02-06
159
Participants Needed
1
Research Sites
226 weeks
Total Duration
On this page
Sponsors
L
Louis Bherer
Lead Sponsor
C
Canadian Institutes of Health Research (CIHR)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The ACTIONcardioRisk trial is designed to investigate the effect of aerobic and progressive resistance training exercises combined with cognitive training, on neurocognitive functioning of sedentary older adults with and without cardiovascular risk factors.
CONDITIONS
Official Title
A Combined Multidomain Intervention to Prevent Cognitive Decline Associated With Cardiovascular Risk Factors.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult aged 60 and older
- Normal or corrected vision and normal hearing for their age range
- No cognitive impairment (Mini-Mental State Examination - MMSE 65 25)
- Inactive (< 150 min of physical activity per week)
You will not qualify if you...
- MMSE 64 24 or diagnosis of dementia
- Uncontrolled psychological or psychiatric condition within the past 6 months
- Neurological disease
- Severe exercise intolerance
- Respiratory disease such as asthma or COPD
- Excessive alcohol consumption (> 15 drinks/week)
- Documented cerebral, peripheral or coronary atherosclerotic disease
- Chronic systolic or diastolic heart failure
- Symptomatic aortic stenosis
- Atrial fibrillation
- Automatic implantable defibrillator or permanent pacemaker
- Malignant exertional arrhythmias
- Non-cardiopulmonary limitation to exercise such as arthritis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Preventive medicine and physical activity centre (centre EPIC), Montreal Heart Institute
Montreal, Quebec, Canada, H1T1N6
Actively Recruiting
Research Team
L
Louis Bherer, PhD
CONTACT
A
Anil Nigam, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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