Actively Recruiting
Prospective Research Rare Kidney Stones (ProRKS)
Led by Mayo Clinic · Updated on 2025-08-06
220
Participants Needed
11
Research Sites
530 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to determine the natural history of the hereditary forms of nephrolithiasis and chronic kidney disease (CKD), primary hyperoxaluria (PH), cystinuria, Dent disease and adenine phosphoribosyltransferase deficiency (APRTd) and acquired enteric hyperoxaluria (EH). The investigator will measure blood and urinary markers of inflammation and determine relationship to the disease course. Cross-comparisons among the disorders will allow us to better evaluate mechanisms of renal dysfunction in these disorders.
CONDITIONS
Official Title
Prospective Research Rare Kidney Stones (ProRKS)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of primary hyperoxaluria
- Diagnosis of enteric hyperoxaluria
- Diagnosis of Dent Disease
- Diagnosis of Cystinuria
- Diagnosis of adenine phosphoribosyltransferase deficiency (APRTd)
- Diagnosis of Lowe Syndrome
- Diagnosis of Dent Disease Carrier
You will not qualify if you...
- Prior renal failure
- History of liver and/or kidney transplant
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 11 locations
1
University of Alabama @ Birmingham
Birmingham, Alabama, United States, 35294
Not Yet Recruiting
2
Mayo Clinic Jacksonville
Jacksonville, Florida, United States, 32224
Not Yet Recruiting
3
Children's Memorial Hospital
Chicago, Illinois, United States, 60614
Not Yet Recruiting
4
Children's Hospital, Harvard Medical School
Boston, Massachusetts, United States, 02115
Not Yet Recruiting
5
Mayo Clinic Hyperoxaluria Center
Rochester, Minnesota, United States, 55905
Actively Recruiting
6
New York University
New York, New York, United States, 10010
Not Yet Recruiting
7
Cincinnati Children's Hosptial Medical Center
Cincinnati, Ohio, United States, 45229
Not Yet Recruiting
8
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19104
Not Yet Recruiting
9
Hosptial of Sick Children
Toronto, Ontario, Canada, M5G 1X8
Not Yet Recruiting
10
Landspitali Universtiy Hospital
Reykjavik, Iceland
Not Yet Recruiting
11
Shaare Zedek Medica Center
Jerusalem, Israel
Not Yet Recruiting
Research Team
B
Barb Seide
CONTACT
J
Julie Olson, RN
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
7
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