A Prospective Randomized Controlled Study on the Treatment of Cystic Lymphatic Malformation Based on Indocyanine Green-fluorescence Imaging

What this Trial Is About

This research aims to explore the role of indocyanine green-fluorescence imaging in diagnosing and treating cystic lymphatic malformation (cLM) in children. The study will compare this imaging approach with traditional surgical methods to provide clearer scientific evidence for future treatments and better understand the disease's development. Participants are divided into groups receiving different treatments, including inflow occlusion assisted by indocyanine green-fluorescence imaging combined with perforation of septation and sclerotherapy, perforation of septation and sclerotherapy alone, indocyanine green-guided partial resection and sclerotherapy, or partial resection and sclerotherapy. Those in the imaging groups receive special guidance during surgery using the indocyanine green method, while control groups receive traditional methods. During the study, researchers will evaluate cure rates and treatment effectiveness at one and three months after treatment, along with how often treatments are needed over six months. Secondary outcomes include wound infection, delayed healing, pigmentation, and patient scores six months post-treatment. Participants will be followed for three to six months to monitor results and side effects.

A Prospective Study on the Treatment of cLM Based on ICG Imaging