Study of Radiofrequency Ablation to Treat Benign and Indeterminate Thyroid Nodules and Low-Risk Papillary Thyroid Cancer Tracking Nodule Changes and Quality of Life Over Time

What this Trial Is About

Researchers are observing adults who have been treated with radiofrequency ablation RFA for benign or indeterminate thyroid nodules and low-risk papillary thyroid cancers. The study aims to track changes in thyroid nodule size over time, assess the long-term effectiveness of RFA, and understand the quality of life of patients after this treatment. It also monitors ultrasound features of thyroid nodules and any adverse events related to the procedure. Participants in this observational study undergo ultrasound-guided RFA as part of their clinical care. Researchers collect data about their health and quality of life using questionnaires that ask about symptoms and complaints related to their thyroid condition. The study focuses on patients who have benign nodules causing symptoms, indeterminate nodules, papillary thyroid carcinoma without metastasis, or locally recurrent thyroid cancer smaller than 2 cm. During the study, participants complete health-related quality of life questionnaires over an average of one year. Medical appointments include evaluations of thyroid nodule volume and ultrasound imaging to observe changes after RFA. The study monitors adverse events and gathers detailed patient-reported outcomes, helping to understand the long-term impact and safety of RFA treatment. Participation involves regular assessments until study completion, which may continue through the end of 2030.

Radiofrequency Ablation for Management of Benign/Indeterminate Thyroid Nodules and Low Risk Papillary Thyroid Cancers