Actively Recruiting

Age: 1Year - 100Years
All Genders
ID05981950

Real-world Application of Using Artificial Intelligence in Diagnosing Retinal Diseases

Led by Beijing Tongren Hospital · Updated on 2023-08-08

100000

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate an artificial intelligence algorithm designed to diagnose multiple retinal diseases using real-world fundus photography. The study focuses on conditions such as referral diabetic retinopathy, age-related macular degeneration, possible glaucoma, pathological myopia, retinal vein occlusion, macular hole, macular epiretinal membrane, hypertensive retinopathy, myelinated fibers, retinitis pigmentosa, and other retinal lesions. The goal is to assess the accuracy and effectiveness of this AI tool in a clinical setting. Participants undergo binocular fundus photography using 45-degree field cameras operated by trained personnel. The images are reviewed for quality and then analyzed by the AI algorithm to detect various retinal diseases. The study observes the AI's diagnostic performance without any therapeutic intervention, focusing on its ability to recognize and classify retinal conditions. Throughout the study, researchers collect data on the AI's diagnostic accuracy by measuring sensitivity, specificity, positive and negative predictive values, area under the curve, and F1 score within one month. Participants provide complete identification information and fundus images covering the optic disc and macula. The study continues until August 2029, monitoring the AI's application in routine clinical practice and its potential role in retinal disease diagnosis.

CONDITIONS

Brief Title

Real-world of AI in Diagnosing Retinal Diseases

Who Can Participate

Age: 1Year - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Fundus photography around 45° field covering optic disc and macula
  • Complete identification information
Not Eligible

You will not qualify if you...

  • Insufficient information for diagnosis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 1 month

Participants undergo fundus photography and images are analyzed by an artificial intelligence algorithm to diagnose various retinal diseases.

1 visit (in-person)

Long-term Monitoring

Duration - Up to 1 month

Participants are observed to evaluate the effectiveness and accuracy of the artificial intelligence algorithm in diagnosing retinal diseases.

Follow-up assessments may occur within 1 month

Trial Site Locations

Total: 1 location

1

Wen-Bin Wei

Beijing, Beijing Municipality, China, 100730

Actively Recruiting

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Research Team

W

Wenbin Wei, MD

R

Ruiheng Zhang, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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