Actively Recruiting

Phase Not Applicable
Age: 18Years - 90Years
All Genders
ID04295473

Comparison of Short and Long-term Outcomes in Gastric Cancer Patients Undergoing Reduced Port Versus Traditional Laparoscopic Gastrectomy

Led by Nanchong Central Hospital · Updated on 2025-05-21

160

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the safety and outcomes of reduced port laparoscopic gastrectomy compared to traditional laparoscopic gastrectomy in patients with gastric cancer. This study aims to systematically compare both short-term and long-term results following these surgical approaches. The short-term outcomes include surgical complications, postoperative morbidity, and nutritional status, while the long-term outcomes focus on survival rates. The study involves two groups: one undergoing reduced port laparoscopic gastrectomy, which uses 1 to 3 ports during surgery, and another receiving the standard laparoscopic gastrectomy with 5 ports. These groups are compared to assess differences in surgical and recovery outcomes. The study is non-randomized and single-blinded, with patients assigned to either surgical method. Participants will be monitored for surgical complications, nutrition, and quality of life using the PGSAS-45 scale over several months following surgery. Survival rates at 3 and 5 years will be tracked as primary outcomes. The study includes regular assessments during the first year and follows participants for up to five years to evaluate long-term survival and recovery.

CONDITIONS

Brief Title

Reduced Port Laparoscopic Gastrectomy for Gastric Cancer

Who Can Participate

Age: 18Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically confirmed adenocarcinoma of the stomach, stages T1 to T4
  • Eastern Cooperative Oncology Group performance status of 0 or 1
  • Adequate organ function
  • Age between 18 and 90 years
Not Eligible

You will not qualify if you...

  • Presence of distant metastasis
  • Oesophageal invasion longer than 3 cm
  • Borrmann type 4 or large (more than 8 cm) type 3 carcinoma
  • Previous chemotherapy or radiation therapy for any other malignancies

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surgery and Immediate Post-operative Care

Duration - Hospital stay duration (varies per participant)

Participants undergo either reduced port laparoscopic gastrectomy or standard laparoscopic gastrectomy for gastric cancer and receive immediate post-operative care.

1 surgery visit and several in-hospital post-operative assessments

Post-operative Follow-up

Duration - Up to 12 months

Participants are monitored for post-operative morbidity, nutritional status, and quality of life following surgery.

Multiple follow-up visits over 12 months

Long-term Monitoring

Duration - Up to 5 years

Participants are followed to assess long-term survival outcomes up to 5 years after surgery.

Periodic visits for survival assessments

Trial Site Locations

Total: 1 location

1

Yunhong Tian

Nanchong, Sichuan, China, 637000

Actively Recruiting

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Research Team

Y

Yunhong Tian, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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