Actively Recruiting

Phase Not Applicable
All Genders
ID07115303

Results of Laparoscopic Appendectomy With Application of Clips Versus Ligature for Stump Closure: A Comparative Study

Led by Sohag University · Updated on 2025-08-11

80

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating two different methods for closing the appendicular stump during laparoscopic appendectomies in patients diagnosed with acute appendicitis. The study aims to compare the technical ease, postoperative complications such as fecal fistula, and economic aspects of using clips versus ligature for stump closure. This prospective trial is randomized and does not involve any masking or blinding of participants or investigators. The study involves two groups: one group will have their appendicular stump closed using clips, while the other will have it closed by ligation during laparoscopic appendectomy. Both procedures are performed in patients undergoing surgery for acute appendicitis. The trial will assess outcomes within 24 hours postoperatively to evaluate results related to each closure method. Participants will be monitored closely after surgery, with researchers focusing on postoperative complications and technical details of the procedure. Outcome measures include the immediate results of the appendectomy with either clips or ligature for stump closure, assessed 24 hours after the operation. The study is sponsored by Sohag University and is expected to complete by February 2026, with the participation duration varying depending on individual treatment timelines.

CONDITIONS

Brief Title

Results of Laparoscopic Appendectomy With Application of Clips Versus Ligature for Stump Closure

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Any patient diagnosed with acute appendicitis of any age and of any sex presented to ER of the Department of General, Laparoscopic and Oncologic Surgery Department, Sohag University Hospital will be enrolled in this study.
Not Eligible

You will not qualify if you...

  • Patients with complicated appendicitis.
  • Patients with unstable cardiac or pulmonary condition.
  • Patients with suspicious crhon's disease or mass intraoperative.

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surgery and Immediate Post-operative Care

Duration - Up to 24 hours postoperative

Participants undergo laparoscopic appendectomy with stump closure by either clips or ligature.

1 surgical procedure and immediate post-operative observation

Trial Site Locations

Total: 1 location

1

Sohag university hospital

Sohag, Egypt

Actively Recruiting

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Research Team

A

Ahmed A Abdelreheem, Resident

M

Mohamed M Ali, Professor

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Published Research Related To This Trial

Clips closure versus endoloop ligation in laparoscopic appendectomy: a systematic review and meta-analysis of comparative studies.

Samuel Ho Ting Poon, Sui Yuen Law, Alex Ting Yeung Lai

https://pubmed.ncbi.nlm.nih.gov/37811063