Observing Right Heart Function Changes During Fluid Treatment in Critically Ill Adults and Their Relation to Venous Congestion

What this Trial Is About

This research investigates right ventriculo-arterial coupling RVAC during fluid loading in critically ill adults experiencing acute circulatory failure. The study explores how the right ventricle adapts to afterload changes and its role in venous congestion and fluid tolerance. It aims to better understand RVAC alterations, their connection to venous congestion, and the effectiveness of echocardiographic indices in assessing right ventricular function and coupling. Participants are critically ill adults in intensive care who require fluid loading based on their doctors judgment. The study observes routine fluid management without experimental treatments. Echocardiography is performed immediately before and after fluid administration to measure RVAC using parameters such as TAPSETRV ratio and other validated indices. Secondary analyses will evaluate fluid responsiveness, venous congestion, and the relationship between RVAC and clinical outcomes. During the study, patients undergo echocardiographic and hemodynamic assessments recorded in a secure database. Researchers measure changes in RVAC and venous congestion parameters before and after fluid loading. They also analyze factors predicting RVAC deterioration and compare measurement methods. The study monitors organ function, ICU stay length, and mortality, with measurements taken around 30 minutes before and after fluid loading. Participation lasts until all assessments are completed, reflecting standard ICU care.

Right Ventriculo-Arterial Coupling During Fluid Loading in ICU Patients