Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT06841471

Role of Corneal Nerves in Dry Eye Disease

Led by Daniela Nosch · Updated on 2025-03-11

140

Participants Needed

1

Research Sites

40 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to determine whether corneal nerve function and morphology are affected by tear film instability and ocular surface homeostasis loss. Additionally, it seeks to investigate whether these factors vary based on the severity of dry eye symptoms.

CONDITIONS

Official Title

Role of Corneal Nerves in Dry Eye Disease

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of Dry Eye Disease based on the TFOS DEWS II report for the DED group
  • No diagnosis of Dry Eye Disease for the non-DED group
  • Adults aged 18 years or older
Not Eligible

You will not qualify if you...

  • Any systemic disease affecting eye health or nerve function
  • History of injury or surgery on the front or back part of the eye affecting corneal structure or physiology
  • Regular use of systemic or eye medications affecting the tear film, except dry eye medications
  • Using eye drops or makeup on the day of measurement
  • Contact lens wearers must avoid lenses for 1 week before the first appointment
  • Participants using dry eye medications must use only preservative-free eye drops on examination days

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Institute of Optometrym FHNW

Olten, Switzerland, 4600

Actively Recruiting

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Research Team

D

Daniela S Nosch, BSc MSc PhD

CONTACT

E

Emanuele Käser, BSc MSc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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