Combined adductor canal (ACB) and sacral erector spinae plane (S-ESP) blocks for total knee arthroplasty pain in hemophilic arthropathy.
Francesco Marrone, Pierfrancesco Fusco, Saverio Paventi...
https://pubmed.ncbi.nlm.nih.gov/39600436Actively Recruiting
Age: 18Years +
All Genders
ID07017400
Effectiveness of the Sacral Erector Spinae Plane (ESP) Block in Total Knee Arthroplasty: A Prospective Observational Study
Led by San Giovanni di Dio Hospital · Updated on 2025-08-28
126
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effectiveness and recovery outcomes of two combinations of locoregional anesthesia in adults over 18 years old undergoing unilateral total knee arthroplasty (TKA) under spinal anesthesia. The study compares the combination of adductor canal block (ACB) with sacral erector spinae plane (ESP) block to ACB combined with iPACK block. It aims to determine whether the ACB plus sacral ESP block provides effective pain relief and postoperative recovery. Participants receive spinal anesthesia and multimodal postoperative pain management, including paracetamol and rescue tramadol. The sacral ESP block is administered at the S2 level using ultrasound guidance and ropivacaine, while ACB and iPACK blocks follow standard protocols. Patients already receiving ACB plus sacral ESP block as part of their care will be observed for up to 48 hours after surgery. During the study, researchers will monitor recovery quality using the QoR-15 score at 24 hours, measure pain levels at rest and during movement over 48 hours, track time to first mobilization, analgesic consumption, and patient satisfaction. They will also watch for any complications related to the nerve blocks. The study lasts up to 30 months, and all data collection respects patient privacy and ethical standards.
CONDITIONS
Brief Title
The Sacral Erector Spinae Plane Block in Total Knee Arthroplasty
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Adults over 18 years old
- ASA physical status I to III
- Scheduled for unilateral total knee arthroplasty with expected hospitalization longer than 24 hours
You will not qualify if you...
- Refusal to give consent
- Allergy to local anesthetics
- Contraindications to spinal or regional anesthesia
- Coagulation disorders
- Use of anticoagulation or antiaggregation medications
- Dementia or severe cognitive impairment
- ASA physical status greater than III
- Ongoing infection
- Emergency surgeries
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Surgery and Immediate Post-operative Care
Duration - Hospitalization longer than 24 hours
Participants undergo unilateral total knee arthroplasty under spinal anesthesia with regional nerve blocks for postoperative pain control.
1 hospitalization period including surgery
Post-operative Follow-up
Duration - 48 hours post-surgery
Participants are observed for recovery quality, pain levels, analgesic use, and time to mobilization during the first 48 hours after surgery.
Assessments during hospitalization up to 48 hours
Trial Site Locations
Total: 1 location
1
San Giovanni Crotone Hospital
Crotone, Italy
Actively Recruiting
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Research Team
T
Tommaso Sorrentino, Anesthesiology
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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Published Research Related To This Trial
A unilateral single level sacral erector spinae plane block for total knee arthroplasty pain.
Francesco Marrone, Carmine Pullano, Saverio Paventi...
https://pubmed.ncbi.nlm.nih.gov/38421355Combined lumbar and sacral erector spinae plane (LS-ESP) block for hip fracture pain and surgery.
Francesco Marrone, Pierfrancesco Fusco, Saverio Paventi...
https://pubmed.ncbi.nlm.nih.gov/38656087Unilateral sacral erector spinae plane block for hip fracture surgery.
F Marrone, S Paventi, M Tomei...
https://pubmed.ncbi.nlm.nih.gov/38187935The effect of sacral erector spinae plane block on the quality of recovery after total hip arthroplasty: a prospective, randomized, controlled, multicenter study.
Muhammed H Satici, Mahmut S Tutar, Yasin Tire...
https://pubmed.ncbi.nlm.nih.gov/39495168A new technique for sensory blockage of posterior branches of sacral nerves: Ultrasound guided sacral erector spinae plane block.
Serkan Tulgar, Ozgur Senturk, David Terence Thomas...
https://pubmed.ncbi.nlm.nih.gov/30999197Pain management after total knee arthroplasty: PROcedure SPEcific Postoperative Pain ManagemenT recommendations.
Patricia M Lavand'homme, Henrik Kehlet, Narinder Rawal...
https://pubmed.ncbi.nlm.nih.gov/35852550