Actively Recruiting
Efficacy of the Erector Spinae Plane Block for Persistent Back Pain in Patients With Ankylosing Spondylitis
Led by Marmara University · Updated on 2026-06-08
15
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Ankylosing spondylitis is a chronic inflammatory disease mainly affecting the spine and sacroiliac joints, causing persistent back pain and stiffness. This research aims to evaluate the effects of the erector spinae plane block, a regional pain-relief technique, on patients who have controlled disease activity under treatment but continue to experience persistent back pain. The study addresses an important need for additional pain management options beyond standard therapies. The erector spinae plane block procedure is performed under ultrasound guidance by injecting a combination of local anesthetic and steroid into a specific muscle plane in the back. This is done twice within one week by experienced specialists. Patients will undergo this procedure and be followed up at baseline, 2 weeks, and 2 months to assess changes in pain and clinical outcomes. Participants will have assessments at three timepoints to measure pain severity, disease activity, spinal mobility, functional status, and back pain-related function. Tools such as the Numeric Rating Scale and various ankylosing spondylitis indices will be used. The study involves regular monitoring of these outcomes to understand the impact of the intervention over two months after treatment.
CONDITIONS
Brief Title
Efficacy of the Erector Spinae Plane Block for Persistent Back Pain in Patients With Ankylosing Spondylitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 65 years
- Diagnosis of ankylosing spondylitis according to the Modified New York Criteria
- Ongoing treatment with controlled disease activity but persistent back pain
- Willingness to participate in the study
You will not qualify if you...
- Body mass index (BMI) greater than 35 kg/m8
- History of thoracic surgery
- Intellectual disability or mental retardation
- Major psychiatric comorbidity
- Congenital spinal anomaly
- Pregnancy
- History of bleeding diathesis
- Active local and/or systemic infection
- Known allergy to the medications to be injected
- Hemodynamic instability
- Active phase of the disease (elevated acute phase reactants, active arthritis findings, etc.)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 week
Participants receive two erector spinae plane block procedures within one week to reduce persistent back pain associated with ankylosing spondylitis.
2 treatment sessions within one week
Duration - 2 months
Participants are assessed for pain severity, disease activity, functional status, and spinal mobility at 2 weeks and 2 months after the treatment.
2 visits (in-person) at 2 weeks and 2 months post-treatment
Trial Site Locations
Total: 1 location
1
Marmara University Faculty of Medicine Pendik Training and Research Hospital
Istanbul, Pendik, Turkey (Türkiye)
Actively Recruiting
Research Team
F
Fatma B Akdağ, Research Assistant
S
Savaş Şencan, Associate Professor
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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