Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT06843005

Serial Coronary CTA-based Plaque Progression Detection for Management of Coronary Heart Disease

Led by Zhang longjiang,MD · Updated on 2026-03-24

3100

Participants Needed

1

Research Sites

200 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The primary objective of this study is to evaluate whether a management strategy based on coronary computed tomography angiography (CCTA) for patients with non-obstructive coronary artery disease can improve the LDL-C target achievement rate compared to a traditional management strategy without follow-up CCTA, thereby reducing the incidence of major adverse cardiovascular and cerebrovascular events over a 3 years period, including all-cause mortality, myocardial infarction, ischemia driven revascularation and stroke.

CONDITIONS

Official Title

Serial Coronary CTA-based Plaque Progression Detection for Management of Coronary Heart Disease

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 80 years old
  • Diagnosis of non-obstructive coronary artery disease for at least 2 years
  • Willingness to undergo follow-up CCTA examinations and comply with follow-up observations
Not Eligible

You will not qualify if you...

  • History of acute coronary syndrome or prior PCI/CABG
  • Previous major adverse cardiovascular or cerebrovascular events
  • Prior follow-up CCTA or DSA examinations before enrollment
  • Severe liver or kidney dysfunction
  • Contraindications to CCTA examinations
  • Poor quality or missing initial CCTA images or data

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Research Institute Of Medical Imaging Jinling Hospital

Nanjing, Jiangsu, China, 210018

Actively Recruiting

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Research Team

L

Longjiang Zhang, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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