Actively Recruiting

Early Phase 1
Age: 18Years - 45Years
All Genders
Healthy Volunteers
NCT05219799

Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

Led by University of Missouri-Columbia · Updated on 2025-05-29

72

Participants Needed

1

Research Sites

172 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this project is to examine key mechanisms contributing to sex-differences in hypoxic vasodilation and the impact of obesity, with particular emphasis on the sympathetic nervous system.

CONDITIONS

Official Title

Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

Who Can Participate

Age: 18Years - 45Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Body mass index (BMI) greater than 18 kg/m2
  • Age between 18 and 45 years
Not Eligible

You will not qualify if you...

  • Pregnancy or breastfeeding
  • Diagnosed sleep apnea or apnea-hypopnea index (AHI) greater than 10 events per hour
  • Current smoking or nicotine use
  • Increased risk of bleeding, clotting disorders, or use of anticoagulation therapy
  • Nerve or neurological diseases
  • Cardiovascular, liver, kidney, or respiratory diseases
  • Blood pressure equal to or higher than 140/90 mmHg
  • Diabetes or polycystic ovarian syndrome
  • Communication barriers
  • Use of prescription medications or sensitivity to lidocaine

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Missouri

Columbia, Missouri, United States, 65211

Actively Recruiting

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Research Team

J

Jacqueline K Limberg, Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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