Actively Recruiting

Phase Not Applicable
Age: 1Month - 16Years
All Genders
ID07307027

Could a Stepwise Enteral Nutritional Algorithm Affect Patient's Outcome in Pediatric Intensive Care Units? An Interventional Study

Led by Ain Shams University · Updated on 2026-01-16

80

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate the effectiveness and patient outcomes after introducing a stepwise enteral nutrition algorithm in the Pediatric Intensive Care Unit (PICU). The study focuses on critically ill children, who are vulnerable to malnutrition due to limited body reserves and the stress of critical illness. The study compares outcomes before and after implementing this protocol to assess its impact on nutritional delivery and patient health. The study includes two phases: a pre-implementation phase with 40 patients receiving standard nutritional care and a post-implementation phase with 40 patients managed under the new stepwise enteral nutritional algorithm. The algorithm guides nutritional assessment, feeding initiation within 4 hours of admission when possible, feeding advancement, and management of feeding intolerance symptoms such as vomiting, diarrhea, and abdominal distention. It also standardizes fasting times before procedures to reduce unnecessary interruptions. Participants will undergo nutritional assessments including weight and growth measurements and be monitored for time to start enteral feeding, time to reach energy goals, and frequency of feeding interruptions. Clinical outcomes such as length of PICU stay, duration of mechanical ventilation, and survival will also be recorded. Safety measures include monitoring feeding intolerance and aspiration risks. Data from both phases will be compared to evaluate the algorithm’s effect, with assessments continuing up to 28 days from admission.

CONDITIONS

Brief Title

Stepwise Enteral Nutritional Algorithm and Patient Outcomes in Pediatric Intensive Care Units

Who Can Participate

Age: 1Month - 16Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Critically ill infants and children admitted to the Pediatric Intensive Care Units
  • Age from 1 month to 16 years (males up to 14 years, females up to 16 years)
Not Eligible

You will not qualify if you...

  • Patients discharged or died within 24 hours of admission
  • Patients with acute pancreatitis
  • Patients with esophageal perforation
  • Patients with a known metabolic disorder
  • Patients requiring a ketogenic diet
  • Patients with Short Bowel Syndrome

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Up to 28 days from admission

Participants receive enteral nutrition according to either the standard care practices or the new stepwise enteral nutritional algorithm designed to optimize feeding initiation, advancement, and management of feeding intolerance in the Pediatric Intensive Care Unit.

Visits occur as part of ongoing Pediatric Intensive Care Unit care with nutritional assessments upon admission and monitoring during the stay

Follow-up

Duration - Up to 28 days from admission

Participants are observed for clinical outcomes including length of stay in the Pediatric Intensive Care Unit and complications related to nutrition during their stay.

Monitoring occurs during the Pediatric Intensive Care Unit stay

Trial Site Locations

Total: 1 location

1

Ain Shams University

Cairo, Abbasia, Egypt, 11591

Actively Recruiting

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Research Team

M

Mohamed A Mohamed, MSc, MB Bch

M

Mervat G Mervat, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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