Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT06144476

Study of Inflammatory and Physiological Profiles of Healthy and Diseased Lung

Led by Guy's and St Thomas' NHS Foundation Trust · Updated on 2024-02-28

230

Participants Needed

1

Research Sites

290 weeks

Total Duration

On this page

Sponsors

G

Guy's and St Thomas' NHS Foundation Trust

Lead Sponsor

K

King's College London

Collaborating Sponsor

AI-Summary

What this Trial Is About

There are over 700,000 UK hospital admissions every year with lung disease symptoms. Two of the most common lung diseases contributing to these numbers are asthma and chronic obstructive pulmonary disease (COPD). The immunopathology of these diseases is not fully understood. Matched samples from the respiratory tract and circulation will be used to identify immune patterns throughout the respiratory system to elucidate the immunopathology of airway disease.

CONDITIONS

Official Title

Study of Inflammatory and Physiological Profiles of Healthy and Diseased Lung

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Participant is willing and able to give informed consent for participation in the study
  • Aged 18 years or above
  • Patient with known or suspected airway disease
  • Healthy volunteer considered to be in good health with no significant comorbidity such as immune disorder or cancer
Not Eligible

You will not qualify if you...

  • Known or suspected current pulmonary tuberculosis, HIV, Hepatitis B Virus, or Hepatitis C Virus
  • Surgery within the preceding 6 weeks
  • Participants who are pregnant
  • History of psychiatric, medical, or surgical disorders that may interfere with sample collection, bronchoscopy, study completion, or data collection
  • Alcohol or recreational drug abuse
  • Diagnosis of immunodeficiency requiring treatment
  • Unable to provide written informed consent
  • Unable to read or write English
  • Considered by the investigator to be an unsuitable candidate for the study

AI-Screening

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Trial Site Locations

Total: 1 location

1

Guy's & St Thomas' NHS Foundation Trust

London, United Kingdom, SE1 9RT

Actively Recruiting

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Research Team

G

Gillian Radcliffe, MRes

CONTACT

S

Steven Cass, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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