Actively Recruiting
Study of New Magnetic Resonance Imaging Methods of the Brain
Led by National Institute of Neurological Disorders and Stroke (NINDS) · Updated on 2026-05-12
1100
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this investigation is to develop improved magnetic resonance imaging (MRI) techniques and hardware for studying brain function. MRI is a diagnostic tool that provides information about brain chemistry and physiology. This study will evaluate new MRI methods for monitoring blood flow to regions of the brain in response to simple tasks. The MRI machine used in this study is more powerful than those in most hospitals, permitting a higher visual resolution. Normal healthy volunteers over 18 years old may be eligible for this study. Candidates will be screened with a medical history and questionnaire, and a neurological examination. Study participants will have a yearly MRI scan. For this procedure, the subject lies on a stretcher that is moved into a donut-shaped machine with a strong magnetic field. A lightweight circular or rectangular coil-a device that improves the quality of the images-may be placed on the head. The scan time varies from 20 minutes to 3 hours; most scans last between 45 and 90 minutes. During the scan, the subject may perform simple tasks, such as listening to tapes, tapping a finger, moving a hand, watching a screen, or smelling a fragrance. More complex tasks may require thinking about tones or pictures and responding to them by pressing buttons. Information from this study will be used to develop better imaging methods that will, in turn, permit a greater understanding of normal and abnormal brain behaviors. ...
CONDITIONS
Official Title
Study of New Magnetic Resonance Imaging Methods of the Brain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age and older
- In good general health
- Able to understand the procedures and give informed consent
You will not qualify if you...
- Presence of metal implants or objects incompatible with MRI, such as pacemakers, aneurysm clips, metallic prostheses, certain orthopedic implants, shrapnel, or metal fragments in the eye
- Claustrophobia
- Inability to lie comfortably for up to 120 minutes
- Prior brain surgery or traumatic head trauma
- Migraines requiring medication
- History of hospitalization for psychiatric disorders
- Medical conditions requiring physiological monitoring during scan, such as pulmonary or airway disease, heart failure, coronary artery disease, uncontrolled hypertension
- Medical conditions that could cause emergency situations during MRI
- Hearing problems that hinder tolerance of scanner noise
- Pregnancy
- Body or makeup tattoos (evaluated case-by-case)
- Sleep apnea diagnosis
- Neurological disorders such as stroke, Parkinson's disease, epilepsy
- Membership in the NINDS Laboratory of Functional and Molecular Imaging
- Presence of gold dental crowns for 7T MRI
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
Research Team
J
Jeffrey H Duyn, Ph.D.
CONTACT
A
Alan P Koretsky, Ph.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here