Actively Recruiting

Age: 18Years +
All Genders
ID05768269

A Long-Term Follow-up Study for Subjects Previously Treated With A Century Therapeutics Cellular Therapy Product

Led by Century Therapeutics, Inc. · Updated on 2025-06-25

375

Participants Needed

7

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to collect long-term safety and survival information from people who were treated previously with cellular therapy products in a Century Therapeutics-sponsored study. It focuses on monitoring any late side effects or risks that may arise after such treatments, especially those involving induced pluripotent stem cell (iPSC)-derived, genome-edited cellular therapies. The study helps understand long-term outcomes related to these advanced cellular treatments for hematological and solid tumor malignancies. Participants who received at least one dose of these cellular therapy products in earlier eligible Century trials will be followed for up to 180 months after their last treatment. This is an observational study with no new treatments given. During this time, researchers will track safety events, survival, and the persistence of the cellular product in the body. Throughout the study, participants will attend scheduled visits for safety monitoring, including checking for any special adverse events and serious side effects possibly related to the cellular therapy. Researchers will also observe overall survival and measure how long the cellular product remains in the participant. The study involves no intervention and continues until 180 months or death, whichever comes first.

CONDITIONS

Brief Title

A Study for Participants Previously Treated With Century Therapeutics Cellular Therapy Product

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participant has provided written informed consent prior to any long-term follow-up study procedures
  • Participants received at least one treatment with a cellular therapy product in an eligible index trial
  • Participant was withdrawn, early discontinued, or completed an eligible index trial
  • Participant is willing and able to comply with scheduled visits, study plan, and other study procedures
Not Eligible

You will not qualify if you...

  • This study has no exclusion criteria

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Long-term Monitoring

Duration - Up to 180 months

Participants who have previously received a cellular therapy product in an eligible trial will be followed for safety and survival outcomes for up to 180 months.

Trial Site Locations

Total: 7 locations

1

Banner MD Anderson Cancer Center

Gilbert, Arizona, United States, 85234

Not Yet Recruiting

2

University of Southern California - Norris Comprehensive Cancer Center

Los Angeles, California, United States, 90033

Not Yet Recruiting

3

University of Maryland Medical Center

Baltimore, Maryland, United States, 21201

Actively Recruiting

4

Corewell Health

Grand Rapids, Michigan, United States, 49503

Not Yet Recruiting

5

Levine Cancer Institute

Charlotte, North Carolina, United States, 28204

Actively Recruiting

6

University of Cincinnati Medical Center

Cincinnati, Ohio, United States, 45229

Actively Recruiting

7

Swedish Cancer Institute

Seattle, Washington, United States, 98104

Actively Recruiting

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Research Team

C

Century Therapeutics Clinical Team

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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