Actively Recruiting
Cell Therapy for Osteoarthritis
Led by Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust · Updated on 2026-01-08
650
Participants Needed
2
Research Sites
N/A
Total Duration
On this page
Sponsors
R
Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Lead Sponsor
K
Keele University
Collaborating Sponsor
AI-Summary
What this Trial Is About
This observational study evaluates the effectiveness of cell therapy for treating osteoarthritis. It compares patients who have undergone Autologous Chondrocyte Implantation (ACI) surgery with those who have not had this surgery to understand if surgical treatment of cartilage defects can prevent osteoarthritis later in life. Participants include a group who had ACI surgery at least 10 months before joining the study and a control group who did not have ACI. There are no drugs or other interventions involved as this is an observational comparison. Participants will complete a Cell Therapy Questionnaire at least fifteen months after their operation to assess outcomes. The study collects information to better understand long-term effects of ACI surgery on osteoarthritis progression. The total participation duration varies, and the research team will monitor responses to evaluate the effectiveness of cell therapy over time.
CONDITIONS
Brief Title
Does Surgical Treatment of Cartilage Defects Prevent Osteoarthritis in Later Life?
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients who have had Autologous Chondrocyte Implantation (ACI) surgery
- Patients receiving an alternative treatment for osteoarthritis
You will not qualify if you...
- Anyone who does not meet the inclusion criteria
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - At least 15 months post operation
Participants who have had surgery or alternative treatment are observed to assess outcomes related to osteoarthritis.
1 to 2 visits depending on questionnaire completion
Trial Site Locations
Total: 2 locations
1
The Robert Jones and Agnes Hunt Orthopaedic Hospital
Oswestry, United Kingdom, Sy10 7AG
Actively Recruiting
2
Robert Jones and Agnes Hunt Orthopaedic hospital
Oswestry, United Kingdom
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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