Actively Recruiting

Phase Not Applicable
Age: 35Years - 85Years
All Genders
NCT07139093

Testing of an Interface for Synchronizing tACS-DBS With a Phase-locked-loop

Led by Universitätsklinikum Hamburg-Eppendorf · Updated on 2026-04-03

2

Participants Needed

1

Research Sites

61 weeks

Total Duration

On this page

Sponsors

U

Universitätsklinikum Hamburg-Eppendorf

Lead Sponsor

U

University of Twente

Collaborating Sponsor

AI-Summary

What this Trial Is About

The investigators aim to test an interface to phase-lock transcranial alternating current stimulation (tACS) and deep brain stimulation (DBS) for future studies investigating the effects of different time-lags between DBS and tACS on the behavioural and neural level. To test if the interface works in patients with DBS, the investigators record EEG during synchronized tACS-DBS in several patients. The investigators hypothesize that they can apply tACS at the desired phase-lags relative to DBS pulses and confirm this with EEG measurements of the DBS and tACS artifact.

CONDITIONS

Official Title

Testing of an Interface for Synchronizing tACS-DBS With a Phase-locked-loop

Who Can Participate

Age: 35Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Provision of written informed consent by the patient
  • Age 35 - 85
  • Patient groups: Parkinson's disease, essential tremor, dystonia
  • More than 3 months after surgery for DBS
Not Eligible

You will not qualify if you...

  • Epilepsy or history of seizures
  • Existence of heart pacemaker or other metal implants in the body (except DBS)
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Medical Center Hamburg-Eppendorf

Hamburg, Germany, 20246

Actively Recruiting

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Research Team

B

Bettina C. Schwab, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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Testing of an Interface for Synchronizing tACS-DBS With a Phase-locked-loop | DecenTrialz