Actively Recruiting

Age: 18Years +
All Genders
NCT06178822

Towards Novel BIOmarkers to Diagnose SEPsis on the Emergency Room

Led by Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC) · Updated on 2025-10-02

3300

Participants Needed

3

Research Sites

205 weeks

Total Duration

On this page

Sponsors

A

Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC)

Lead Sponsor

A

Amsterdam UMC, location VUmc

Collaborating Sponsor

AI-Summary

What this Trial Is About

Objectives: 1. To compare the immune response of patients with or without sepsis presenting to the ED with a(n) (suspected) infection. 2. To determine immune response aberrations that are associated with an increased risk of developing sepsis in patients presenting to the ED with a(n) (suspected) infection without sepsis. 3. To determine the long term cognitive and physical sequelae of sepsis after admission.

CONDITIONS

Official Title

Towards Novel BIOmarkers to Diagnose SEPsis on the Emergency Room

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or higher
  • Presentation at the Emergency Department (ED)
  • Clinical suspicion of infection or earlier confirmed infection
  • Modified Early Warning Score (MEWS) of 2 or higher
Not Eligible

You will not qualify if you...

  • No informed consent given

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Flevoziekenhuis

Almere Stad, Flevoland, Netherlands, 1315RA

Not Yet Recruiting

2

Amsterdam UMC, location VUMC

Amsterdam, North Holland, Netherlands, 1081HZ

Actively Recruiting

3

Amsterdam UMC, location AMC

Amsterdam, North Holland, Netherlands, 1105AZ

Actively Recruiting

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Research Team

O

Oren Turgman, MD, MsC

CONTACT

E

Evelien Reijnders, MD, MsC

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Towards Novel BIOmarkers to Diagnose SEPsis on the Emergency Room | DecenTrialz