Personalized CPAP Treatment to Improve Blood Sugar Control in Adults with Obstructive Sleep Apnea

What this Trial Is About

This research aims to improve metabolic health by studying how treatment of obstructive sleep apnea OSA affects blood sugar control. It focuses on patients with OSA who also have diabetes or prediabetes, a common combination that can worsen health. The study seeks to answer key questions about how well continuous positive airway pressure CPAP therapy controls blood sugar, especially when sleep duration and long-term diabetes are considered. The project uses a large group of 600 patients followed for 18 months and collects detailed data on CPAP use, sleep patterns, other health conditions, lifestyle, and biomarkers related to metabolism. Participants diagnosed with OSA and planned for CPAP treatment will be followed over 12 months. The study does not involve experimental treatments but observes patients using CPAP as prescribed. Researchers will carefully track CPAP adherence and sleep duration, alongside various health measures. During the study, participants will undergo regular assessments of blood sugar control using measures like insulin resistance, glycated hemoglobin HbA1c, blood glucose, insulin levels, and blood fats such as triglycerides and cholesterol. Data collection will continue from enrollment through the 12-month treatment period. The goal is to develop personalized treatment strategies for better glycemic control in patients using CPAP for OSA.

Treatment of Sleep Apnea to Improve Metabolic Health