Actively Recruiting

Phase Not Applicable
Age: 45Years - 65Years
All Genders
Healthy Volunteers
NCT06012227

Assessment Metabolic Flexibility in Middle-aged Individuals: The Nutritional Impact of Cheese Consumption

Led by University of Cagliari · Updated on 2023-08-30

105

Participants Needed

1

Research Sites

256 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of the study will be to evaluate the impact of consumption of meat and dairy products from extensive or intensive farming on apparently healthy individuals aged between 45 and 65 years, a stage of life associated with reduced metabolic flexibility and changes in lipid metabolism. The study will analyze: 1. The transcription factor PPAR-α determined by the gene expression of PPAR-α in white blood cells, variations in circulating fatty acid metabolism, and the endocannabinoid system determined by circulating analysis of N-acylethanolamine (NAE), and 2-monoacylglycerols (2-MG); 2. Metabolic flexibility, determined by indirect calorimetry in fasting condition during an incremental exercise; 3. Body composition, determined by bioimpedance analysis, waist circumference, and waist-to-hip ratio.

CONDITIONS

Official Title

Assessment Metabolic Flexibility in Middle-aged Individuals: The Nutritional Impact of Cheese Consumption

Who Can Participate

Age: 45Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Between 45 and 65 years old
  • Body mass index (BMI) less than 27
  • Waist-to-hip ratio less than 0.85 for females and less than 0.98 for males
Not Eligible

You will not qualify if you...

  • Having metabolic diseases
  • Engaging in competitive physical activity
  • Being vegan or vegetarian
  • Having intolerances or allergies to the foods studied

AI-Screening

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Trial Site Locations

Total: 1 location

1

University of Cagliari

Monserrato, Cagliari, Italy, 09042

Actively Recruiting

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Research Team

S

Sebastiano Banni

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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