Actively Recruiting
Trends in the Administration of Tranexamic Acid for Postpartum Hemorrhage
Led by Mahidol University · Updated on 2025-12-22
648
Participants Needed
1
Research Sites
43 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Postpartum hemorrhage (PPH) is the global leading cause of maternal death, with 20-30% of maternal deaths in Thailand linked to hemorrhage. The WOMAN Trial (2017) provided strong evidence that administering tranexamic acid (TXA)within three hours of bleeding onset lowered PPH-related mortality by 31%. Consequently, the World Health Organization (WHO) updated its guidelines, recommending TXA as part of the standard treatment package for all PPH cases. Following this, the use of TXA has been widely adopted globally and increased in Thailand. A recent study at a major Thai university hospital observed a significant increase in TXA administration after 2017. The current study aims to further analyze the recent growth rate of TXA use and its impact on obstetric and perinatal outcomes during cesarean deliveries with PPH.
CONDITIONS
Official Title
Trends in the Administration of Tranexamic Acid for Postpartum Hemorrhage
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients underwent cesarean delivery with primary postpartum hemorrhage
You will not qualify if you...
- Gestational age less than 24 weeks
- No anesthetic record available
- Received tranexamic acid during the antepartum period
- Blood loss less than 1,000 ml
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Siriraj Hospital
Bangkoknoi, Bangkok, Thailand, 10700
Actively Recruiting
Research Team
P
Patchareya Nivatpumin, M.D.
CONTACT
P
Premyuda Matangkarat, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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