Actively Recruiting

Age: 19Years - 80Years
All Genders
NCT06400095

Ventilatory Parameters in Predicting Outcomes in ARDS Patients

Led by CentraCare · Updated on 2024-08-22

50

Participants Needed

1

Research Sites

108 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a single-centre prospective observational study aimed to determine if Pocc (occlusion pressure at 100 msec), TCe ( Expiratory time constant ), Mechanical Stress power, Ventilatory ratio and C20/Cdyn would predict outcomes in patients with moderately severe ARDS (Acute respiratory distress syndrome), who are on mechanical ventilation

CONDITIONS

Official Title

Ventilatory Parameters in Predicting Outcomes in ARDS Patients

Who Can Participate

Age: 19Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with acute respiratory failure needing mechanical ventilation
  • Diagnosis of severe ARDS with PF ratio < 150 and PEEP/CPAP > 5
  • Age between 19 and 80 years
Not Eligible

You will not qualify if you...

  • r2 < 0.95 as monitored on the ventilator
  • Expiratory flow that is not first-order or non-exponential decay
  • Patients requiring nor-epinephrine > 0.1 mcg/kg/min within 2 hours of intubation
  • Patients requiring extracorporeal membrane oxygenation (ECMO)
  • Patients with COPD or pulmonary fibrosis with a premorbid FEV1 < 1.5 L
  • Severe atherosclerotic vascular disease
  • Patients with a chest tube, intra-abdominal hypertension, or risk factors for intra-abdominal hypertension
  • Patients with structural heart disease including pulmonary hypertension (RVSP > 45) and heart failure
  • All comfort care orders in the ICU
  • Patients who underwent tracheostomy

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

St Cloud Hospital

Saint Cloud, Minnesota, United States, 56303

Actively Recruiting

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Research Team

R

Ramakanth Pata, MD FCCP

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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