Comparing Video and Direct Laryngoscopy for Less Invasive Surfactant Administration in Premature Infants Born Before 28 Weeks

What this Trial Is About

Researchers are studying premature infants born between 22 and 28 weeks gestational age who need surfactant, a medicine that helps their lungs. The study compares two methods of visualization during a procedure called less invasive surfactant administration LISA to see which method has a higher success rate on the first attempt and what benefits each method offers. The study involves two groups one uses video laryngoscopy to see the vocal cords and place the catheter, while the other uses direct laryngoscopy without a camera for the same procedure. Both methods aim to deliver surfactant to the infants lungs with minimal invasiveness. Participants are monitored closely during and after the procedure for various factors such as oxygen levels, heart rate, the number of attempts, and any complications like pneumothorax or the need for intubation. The main outcome measured is how often the surfactant is successfully given on the first try. The study follows infants up to 90 days to assess survival and other health outcomes.

Video vs. Direct Laryngoscopy for Less Invasive Surfactant Administration