Actively Recruiting
Virtual Home-based Physical Pre-habilitation in Kidney Transplant Candidates
Led by McGill University Health Centre/Research Institute of the McGill University Health Centre · Updated on 2025-12-03
30
Participants Needed
2
Research Sites
117 weeks
Total Duration
On this page
Sponsors
M
McGill University Health Centre/Research Institute of the McGill University Health Centre
Lead Sponsor
T
The Kidney Foundation of Canada
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this RCT is to address the feasibility of conducting a 12-week virtual pre-habilitation intervention, which includes exercise and education, in kidney transplant candidates. The intervention also includes a 5-month maintenance phase with independent home exercises (maximum of 8 months of intervention/ended early if the participant undergoes a kidney transplant). The main questions it aims to answer are: * estimate the proportion of screened patients who meet eligibility criteria * estimate the proportion of eligible patients who consent to randomization * estimate the proportion of patients who adhere to the interventions * estimate follow-up completion rates * inform the calculation of sample size requirements for a full-scale RCT * assess the acceptability of the intervention by the participants. Participants in the control group will receive usual outpatient care.
CONDITIONS
Official Title
Virtual Home-based Physical Pre-habilitation in Kidney Transplant Candidates
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older with end-stage kidney disease
- Classified as pre-frail, frail, or very frail based on Fried's frailty phenotype
- Accepted or in process of acceptance to the kidney transplant waiting list at MUHC, CHUM, or University of Alberta Hospital
- English or French speakers
- Able to connect to online video sessions independently or with help, or willing to borrow a tablet with internet access
You will not qualify if you...
- Classified as robust (0 points) on Fried's frailty phenotype
- Currently participating in a structured exercise program or another trial
- Waiting for kidney-pancreas or kidney-liver transplant
- Hospitalized during eligibility assessment
- Have cPRA >95% and are on the highly sensitized exchange program with expected long waiting times
- Expected to receive transplant before end of 12-week intervention
- Have significant cognitive impairment
- Have cardiac, musculoskeletal, neuropathy, or neurological conditions that make exercise unsafe
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Centre de recherche - Centre Hospitalier de l'Université de Montréal (CRCHUM)
Montreal, Quebec, Canada, H2X 0A9
Actively Recruiting
2
Research Institute - McGill University Health Centre (RI-MUHC)
Montreal, Quebec, Canada, H4A 3J1
Actively Recruiting
Research Team
T
Tania Janaudis-Ferreira, PhD
CONTACT
A
Amanda Rizk, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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