Five weeks of immersive reminiscence therapy improves autobiographical memory in Alzheimer's disease.
Marie Kirk, Katrine Willemoes Rasmussen, Susanne Bollerup Overgaard...
https://pubmed.ncbi.nlm.nih.gov/30198380/Actively Recruiting
Led by Montefiore Medical Center · Updated on 2025-12-19
50
Participants Needed
1
Research Sites
N/A
Total Duration
Reminiscence therapy is a non-invasive approach that combines social interaction and sharing personal stories to help improve thinking, mood, daily function, quality of life, and reduce apathy in older adults. This research aims to explore how a virtual group reminiscence therapy provided by the Life Story Club LSC can reduce loneliness and apathy in community-dwelling older adults. The study focuses on individuals without dementia who experience loneliness, addressing social connection as a key factor in cognitive health. Participants will join a virtual group reminiscence therapy led by trained Life Story Club facilitators. Groups of 6 to 10 people will meet weekly for one hour over a 12-week period via Zoom, sharing life stories and building community. Sessions will be conducted in English or Spanish, depending on participant preference. The study will assess changes in loneliness and apathy before and after the intervention, and feasibility will be evaluated through enrollment, acceptability, and satisfaction measures. A subset of participants will also take part in interviews to discuss their experience. During the study, participants will complete evaluations of loneliness, apathy, cognitive function, depressive symptoms, sense of meaning and purpose, and social support at baseline, 3 months, and 6 months. The research will track how well participants engage with the therapy and their satisfaction with the program. The total participation duration includes the 12-week intervention and follow-up assessments at 3 and 6 months to measure changes and gather feedback on the therapys impact and feasibility.
CONDITIONS
A Virtual Life Story Club Intervention to Improve Loneliness and Apathy in Community-Dwelling Older Adults
M
Mirnova Ceide, MD
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Montefiore Medical Center
Lead Sponsor
National Center for Advancing Translational Sciences (NCATS)
Collaborating Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | Life Story Club virtual reminiscence group | Usual social activity (no formal reminiscence group) |
|---|---|---|
| What it is | A virtual group reminiscence therapy led by trained facilitators, where older adults meet online weekly for 12 weeks to share life stories and build community. | Unstructured community or social activity for older adults. No formal reminiscence group or facilitated therapy. |
| Primary use | Intended to reduce loneliness and apathy, support social connectedness, and improve psychological well-being. | Social engagement or connection as available, but not specifically aimed at reducing loneliness through reminiscence. |
| How it is given or performed | Facilitators guide a weekly one-hour virtual group meeting using question prompts and structured discussions in English or Spanish. | No structured group sessions or facilitators; community engagement may happen informally through everyday interactions. |
| Evidence status | This specific online reminiscence program is newly under study. No published results yet for this trial. | Group reminiscence therapy in older adults has shown positive effects for loneliness, depressive symptoms, and well-being in meta-analyses and RCTs, while usual social activity is less effective in published studies. |
| Important limitations | The trial is single-group, so there is no direct randomized comparison. Participation requires internet or phone access and English or Spanish fluency, which may limit generalizability. | Usual social activity is not standardized, varies widely by individual, and tends to be less structured or intentional than group reminiscence programs. Effects for loneliness or apathy may not be well-documented in community samples. |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (virtual or in-person) to assess eligibility
Duration - 12 weeks
Participants engage in a virtual group reminiscence therapy intervention called Life Story Club, meeting weekly to share life stories and build community.
Weekly virtual group sessions for 12 weeks
Duration - Up to 6 months after treatment
Participants’ loneliness, apathy, cognition, depressive symptoms, meaning and purpose, and social support are assessed after the intervention at 3 and 6 months.
Assessments at 3 months and 6 months post-intervention
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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Lead Sponsor
National Center for Advancing Translational Sciences (NCATS)
Collaborating Sponsor